ECC3 BioVector?人食管腺癌細(xì)胞株Human Esophageal Adenocarcinoma Cell Line

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BioVector? ECC3 cell line an oesophageal adenocarcinoma model often used to study Barrett's oesophagus progression and gastrointestinal oncology.

BioVector? ECC3 細(xì)胞系數(shù)據(jù)表

參數(shù)	詳細(xì)信息
細(xì)胞名稱	ECC3
物種來源	人類 (Homo sapiens)
組織來源	食管 (Esophagus)
疾病診斷	食管腺癌 (Esophageal Adenocarcinoma)
細(xì)胞形態(tài)	上皮細(xì)胞樣
生長特性	貼壁生長
培養(yǎng)基配方	DMEM/F12 或 RPMI-1640 + 10% 胎牛血清 (FBS)
培養(yǎng)環(huán)境	37°C，5% CO?，恒溫恒濕培養(yǎng)
傳代方法	使用 0.25% Trypsin-EDTA 消化。傳代比例通常為 1:2 至 1:4，每 3-5 天傳代一次。
主要應(yīng)用	食管癌耐藥性研究；腫瘤細(xì)胞侵襲與遷移實(shí)驗(yàn)；胃腸道癌癥基因組學(xué)。
生物安全等級	1 級

English Version: ECC3 Cell Line Datasheet

Parameter	Information
Name	ECC3
Organism	Human (Homo sapiens)
Tissue Source	Esophagus
Disease	Esophageal Adenocarcinoma
Morphology	Epithelial-like
Growth Mode	Adherent
Culture Medium	DMEM/F12 or RPMI-1640 supplemented with 10% Fetal Bovine Serum (FBS)
Culture Conditions	37°C, 5% CO?, humidified atmosphere
Subculturing	Use 0.25% Trypsin-EDTA for detachment; split ratio 1:2 to 1:4 every 3-5 days.
Applications	Drug resistance studies in esophageal cancer; invasion/migration assays; gastrointestinal oncology research.
Biosafety Level	1

Key Characteristics / 關(guān)鍵特征

Clinical Relevance: ECC3 provides a representative model for adenocarcinomas arising in the lower esophagus, which is frequently associated with chronic acid reflux and Barrett's esophagus.
Genetic Profile: Often used in studies investigating p53 mutations and HER2 status in Upper GI cancers.
臨床相關(guān)性： ECC3 為發(fā)生于食管下段的腺癌提供了代表性模型，此類癌癥通常與慢性反流和巴雷特食管相關(guān)。
遺傳特征：常用于研究上消化道癌癥中的 p53 突變和 HER2 表達(dá)狀態(tài)。