ICC18 BioVector?人類肝內(nèi)膽管癌細胞株Human Intrahepatic Cholangiocarcinoma Cell Line

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BioVector? ICC18 細胞系是一株源自人類的肝內(nèi)膽管癌 (Intrahepatic Cholangiocarcinoma) 細胞，是研究膽道系統(tǒng)腫瘤浸潤、轉(zhuǎn)移及藥敏實驗的重要體外模型。

BioVector? ICC18 細胞系數(shù)據(jù)表

參數(shù)	詳細信息
細胞名稱	ICC18 (或 ICC-18)
物種來源	人類 (Homo sapiens)
組織來源	肝臟；肝內(nèi)膽管 (Intrahepatic Bile Duct)
疾病診斷	肝內(nèi)膽管癌 (Intrahepatic Cholangiocarcinoma)
細胞形態(tài)	上皮細胞樣；多角形或鋪路石狀
生長特性	貼壁生長
培養(yǎng)基配方	DMEM 或 DMEM/F12 + 10% 胎牛血清 (FBS) + 1% 雙抗
培養(yǎng)環(huán)境	37°C，5% CO?，恒溫恒濕培養(yǎng)
傳代方法	使用 0.25% Trypsin-EDTA 消化；傳代比例通常為 1:2 至 1:4
主要應(yīng)用	膽管癌靶向藥物篩選、腫瘤血管生成研究、上皮-間充質(zhì)轉(zhuǎn)化 (EMT) 研究
生物安全等級	1 級

Human Intrahepatic cholangiocarcinoma cell line HuCC-T1

BioVector? ICC18 Cell Line Datasheet

Parameter	Information
Name	ICC18 (or ICC-18)
Organism	Human (Homo sapiens)
Tissue Source	Liver; Intrahepatic Bile Duct
Disease	Intrahepatic Cholangiocarcinoma (ICC)
Morphology	Epithelial-like; polygonal or cobblestone appearance
Growth Mode	Adherent
Culture Medium	DMEM or DMEM/F12 supplemented with 10% Fetal Bovine Serum (FBS) and 1% Pen/Strep
Culture Conditions	37°C, 5% CO?, humidified atmosphere
Subculturing	Use 0.25% Trypsin-EDTA for detachment; split ratio 1:2 to 1:4
Applications	Targeted therapy screening, tumor angiogenesis, and EMT studies in cholangiocarcinoma
Biosafety Level	1

Key Characteristics / 關(guān)鍵特征

Tumorigenicity: ICC18 cells are typically tumorigenic and can be used to establish subcutaneous or orthotopic xenograft models in nude mice.
Marker Expression: Often positive for biliary markers such as Cytokeratin 7 (CK7) and Cytokeratin 19 (CK19), confirming their cholangiocyte origin.
成瘤性： ICC18 細胞具有致瘤性，可用于在裸鼠中建立皮下或原位異種移植模型。
標志物表達：通常表達膽管上皮標志物，如細胞角蛋白 7 (CK7) 和細胞角蛋白 19 (CK19)，證實了其膽管細胞來源。