BioVector? NTCC? GIST-T1 人胃腸道間質(zhì)瘤 (GIST) 細(xì)胞系NTCC?

The NTCC? GIST-T1 cell line is an adherent, human gastrointestinal stromal tumor (GIST) cell line derived from a gastric tumor in a Japanese woman. It is a widely used model for studying GIST pathogenesis and drug resistance mechanisms, particularly concerning imatinib mesylate (IM). GIST-T1 Cell Line Datasheet Characteristic English 中文 (Chinese) Organism Homo sapiens (Human) Homo sapiens (人) Tissue Stomach (Gastrointestinal tract) 胃 (胃腸道) Disease Gastrointestinal Stromal Tumor (GIST) 胃腸道間質(zhì)瘤 (GIST) Sex Female 女性 Ethnicity Asian (Japanese) 亞洲 (日本) Morphology Elongated, spindle-shaped, epithelial-like adherent cells 細(xì)長(zhǎng)、紡錘形、上皮樣貼壁細(xì)胞 Growth Properties Adherent monolayer 貼壁單層生長(zhǎng) Doubling Time Approximately 26.59 hours 約 26.59 小時(shí) Key Mutation KIT exon 11 (V560-Y579Δ5 deletion) KIT 外顯子 11 突變 (V560-Y579Δ5 缺失) Immunomarker Strongly immunopositive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫強(qiáng)陽(yáng)性 Biosafety Level 1 (Generally) 1 級(jí) (通常) Culture Conditions Medium: Dulbecco's Modified Eagle's Medium (DMEM) or RPMI 1640 medium, supplemented with 10% to 15% Fetal Bovine Serum (FBS) and antibiotics (e.g., penicillin/streptomycin). Temperature: 37°C CO?: 5% CO? in a humidified incubator Subculture: Cells should be subcultured when they reach 70-90% confluence, using 0.25% trypsin. 中文資料 (Chinese Datasheet) NTCC? GIST-T1 細(xì)胞系是一種貼壁人胃腸道間質(zhì)瘤 (GIST) 細(xì)胞系，源自一名日本女性的胃部腫瘤。它是研究 GIST 發(fā)病機(jī)制和耐藥性機(jī)制（特別是針對(duì)甲磺酸伊馬替尼 (IM)）的常用模型。 GIST-T1 細(xì)胞系參數(shù) 特性 English 中文 (Chinese) 生物體 Homo sapiens (Human) Homo sapiens (人) 組織 Stomach (Gastrointestinal tract) 胃 (胃腸道) 疾病 Gastrointestinal Stromal Tumor (GIST) 胃腸道間質(zhì)瘤 (GIST) 性別 Female 女性 種族 Asian (Japanese) 亞洲 (日本) 形態(tài) Elongated, spindle-shaped, epithelial-like adherent cells 細(xì)長(zhǎng)、紡錘形、上皮樣貼壁細(xì)胞 生長(zhǎng)特性 Adherent monolayer 貼壁單層生長(zhǎng) 倍增時(shí)間 Approximately 26.59 hours 約 26.59 小時(shí) 關(guān)鍵突變 KIT exon 11 (V560-Y579Δ5 deletion) KIT 外顯子 11 突變 (V560-Y579Δ5 缺失) 免疫標(biāo)記 Strongly immunopositive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫強(qiáng)陽(yáng)性 生物安全級(jí)別 1 (Generally) 1 級(jí) (通常) 培養(yǎng)條件 培養(yǎng)基： 使用補(bǔ)充 10% 至 15% 胎牛血清 (FBS) 和抗生素（如青霉素/鏈霉素）的 Dulbecco's Modified Eagle's Medium (DMEM) 或 RPMI 1640 培養(yǎng)基。 溫度： 37°C CO?： 在 37°C、5% CO? 培養(yǎng)箱中培養(yǎng)。 傳代： 當(dāng)細(xì)胞匯合度達(dá)到 70-90% 時(shí)，使用 0.25% 胰蛋白酶進(jìn)行傳代。 BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心 電話:400-800-2947 工作QQ/微信同號(hào):1843439339 網(wǎng)址 www.nedfriskphoto.com

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