NTCC? FU-UrC-1人輸尿管癌細(xì)胞株human ureteral carcinoma cell line

BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心

The NTCC? FU-UrC-1 cell line is a human ureteral carcinoma cell line. It has been widely used in cancer research, particularly in studies related to ureteral cancer.

Key Characteristics:

• Origin: Derived from a human ureteral carcinoma

• Morphology: Epithelial-like cells

• Tumorigenicity: Can form tumors in nude mice

• Genetic Alterations: Characterized by an ASPL-TFE3 gene fusion, a common genetic abnormality in this type of cancer.

Applications in Research:

The FU-UrC-1 cell line has been used in various research areas, including:

• Ureteral cancer research: Studying the molecular mechanisms of ureteral cancer development and progression, particularly those driven by the ASPL-TFE3 fusion.

• Drug development and screening: Evaluating the efficacy and toxicity of potential anticancer drugs.

• Cell biology: Investigating cellular processes such as cell cycle regulation, apoptosis, and signal transduction pathways.

Limitations:

• Immortalized cell line: May not perfectly reflect the behavior of primary tumor cells.

• Potential for genetic drift: Prolonged culture can lead to changes in the cell line's genetic makeup.

生產(chǎn)廠家Supplier:

BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心

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