639V NTCC?人膀胱移行細胞癌細胞株human bladder transitional cell carcinoma cell line

BioVector NTCC質(zhì)粒載體菌株細胞蛋白抗體基因保藏中心

The 639V cell line is a human bladder transitional cell carcinoma cell line. It has been widely used in cancer research, particularly in studies related to bladder cancer.

639V cell line

Key Characteristics:

• Origin: Derived from a human bladder transitional cell carcinoma

• Morphology: Epithelial-like cells

• Tumorigenicity: Can form tumors in nude mice

• Genetic Alterations: Known to harbor genetic alterations, including mutations in the TP53 and RAS genes.

Applications in Research:

The 639V cell line has been used in various research areas, including:

• Bladder cancer research: Studying the molecular mechanisms of bladder cancer development and progression.

• Drug development and screening: Evaluating the efficacy and toxicity of potential anticancer drugs.

• Cell biology: Investigating cellular processes such as cell cycle regulation, apoptosis, and signal transduction pathways.

Limitations:

• Immortalized cell line: May not perfectly reflect the behavior of primary tumor cells.

• Potential for genetic drift: Prolonged culture can lead to changes in the cell line's genetic makeup.

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BioVector NTCC質(zhì)粒載體菌株細胞蛋白抗體基因保藏中心

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