NTCC? CCB人絨毛膜癌細(xì)胞株human choriocarcinoma cell line

BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心

The CCB cell line refers to a specific cell line derived from human choriocarcinoma. This cell line is widely used in research related to cancer biology, particularly in studies focusing on gestational trophoblastic diseases and choriocarcinoma (a rare and aggressive form of cancer that originates in the placenta).

Key Features of the CCB Cell Line:

1. Origin: The CCB cell line was established from a human choriocarcinoma, which is a cancerous tumor that arises from trophoblastic cells of the placenta during pregnancy.

2. Cell Type: The CCB cell line consists of trophoblast-like cells, which are cells that normally form the outer layer of the placenta and help it to implant into the uterine wall.

3. Applications:

   • Cancer Research: The CCB cell line is used to study the biology of choriocarcinoma, including mechanisms of tumorigenesis and metastasis.

   • Drug Testing: It is used in testing various anticancer drugs, especially those targeting trophoblast and placental cancer.

   • Molecular Studies: Researchers study the expression of hormones like hCG (human chorionic gonadotropin), which are typically elevated in choriocarcinoma, to understand their role in cancer progression.

4. Growth and Characteristics: The CCB cell line can be cultured in vitro and is often used in laboratory experiments to investigate cancer-related pathways and therapeutic interventions.

5. Hormonal Production: One notable feature of the CCB cell line is its ability to produce hCG, which is typically found in the blood and urine of pregnant women and is a biomarker for certain types of cancer, particularly gestational trophoblastic diseases.

Use in Research:

The CCB cell line is valuable in oncology research due to its ability to mimic the behavior of choriocarcinoma cells in the laboratory. It serves as a model system for understanding how choriocarcinoma develops and responds to treatments.

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