Nissle 1917-LuxCDABE NTCC?體外熒光表達(dá)大腸桿菌益生菌株-BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心

Nissle 1917 is a strain of Escherichia coli that has been used as a probiotic for over a century.It has a long history of safe use and has been shown to have various health benefits, including improving gut health, boosting immunity, and reducing inflammation.

LuxCDABE is a bacterial operon that encodes enzymes responsible for bioluminescence. When this operon is introduced into a bacterium, it allows the bacterium to emit light. This can be useful for tracking the bacteria in vivo, such as in the gut or in a tumor.

By combining Nissle 1917 with the LuxCDABE operon, researchers can create a bioluminescent probiotic strain that can be used for various applications, such as:

• Tracking the bacteria in the gut: This can be used to study the colonization patterns of the bacteria and to monitor its effects on gut health.

• Imaging tumors: The bioluminescent bacteria can be used to image tumors in vivo, which can help to monitor the progression of the disease and to assess the effectiveness of treatments.

• Delivering drugs: The bacteria can be engineered to produce and deliver therapeutic proteins or drugs to specific tissues.

  
  

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