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首頁(yè) ? OPM-1人源漿細(xì)胞性骨髓瘤細(xì)胞株NTCC? Human Plasma cell myeloma cell line-BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心

OPM-1人源漿細(xì)胞性骨髓瘤細(xì)胞株NTCC? Human Plasma cell myeloma cell line-BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心

  • 價(jià)  格:¥98950
  • 貨  號(hào):NTCC?-5210 OPM-1
  • 產(chǎn)  地:北京
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OPM-1人源漿細(xì)胞性骨髓瘤細(xì)胞株NTCC? Human Plasma cell myeloma cell line-BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心


Cell line nameOPM-1
SynonymsOPM1
AccessionCVCL_5210
Resource Identification InitiativeTo cite this cell line use: OPM-1 (RRID:CVCL_5210)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Characteristics: Produces Ig lambda.
Doubling time: 36-42 hours (PubMed=3926660).
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Heterozygous (DepMap=ACH-000057).

  • Mutation; HGNC; 3690; FGFR3; Simple; p.Lys650Glu (c.1948A>G); ClinVar=VCV000016331; Zygosity=Heterozygous (PubMed=11157491; DepMap=ACH-000057).

  • Mutation; HGNC; 6768; SMAD2; Simple; p.Leu87Arg (c.260T>G); Zygosity=Heterozygous (DepMap=ACH-000057).

  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (DepMap=ACH-000057).

Genome ancestrySource: PubMed=30894373

Origin% genome


African0.52
Native American0
East Asian, North74.49
East Asian, South22.3
South Asian0
European, North0
European, South2.68
DiseasePlasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individualCVCL_1625 ! OPM-2
Sex of cellFemale
Age at sampling56Y
CategoryCancer cell line
STR profileSource(s): Technion Genomics Center

Markers:
AmelogeninX
CSF1PO12,13
D1S165616,17.3
D2S44110
D2S133819,25
D3S135815,18
D5S81813
D7S82012
D8S117910,13
D10S124814
D12S39117,18
D13S31711
D16S5399,13
D18S5113,14,15
D19S43314,14.2
D21S1130,33.2
D22S104511,17
FGA20,21
Penta D9
Penta E12,20,21
TH016,7
TPOX8
vWA14,17

Images

Characterization of the MM.1 human multiple myeloma (MM) cell lines:A  model system to elucidate the characteristics, behavior, and signaling of  steroid-sensitive and -resistant MM cells - ScienceDirect

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BioVector NTCC質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心

E-mail:[email protected]

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