Cell Line Name：NTCC? IL11R STAT3信號(hào)通路穩(wěn)定表達(dá)細(xì)胞株NTCC? Signaling Pathway Stable Cell Line

Target藥物靶點(diǎn)：IL11R STAT3
Cat#貨號(hào):NTCC?-S-IL11R STAT3
Size/Quantity數(shù)量: 1 Flask / 2 Vials
Biosafety Level生物安全級(jí)別: 1
Shipping Info運(yùn)輸方式: RT/Dry Ice
Storage儲(chǔ)存方式: RT/Liquid Nitrogen
Application用途:Reporter
Cellular pathway signaling constitutes key mechanisms that transfer biological information within cells for intracellular responses crucial in many physiological processes, including cell proliferation, differentiation, metabolic control, and apoptosis. Cell signaling pathways are activated when ligands (e.g., cytokines, growth factors, or hormones) bind to specific receptors on the cell surface. Detecting specific stimuli via intracellular signal pathways becomes paramount in interrogating the mechanism of action of the target ligand/receptor interaction for advancing drug discovery and development in many pathophysiologic and pharmacologic mechanisms. BioVector NTCC Inc. offers a comprehensive collection of cell-based pathway indicator assays designed to detect activation or inhibition of complex signal transduction pathways in response to a small molecule or biologic. The assays are based on the established NTCC?PathHunter technology, and feature indicator cell lines used in p Product Highlights Homogeneous Assays – Simple, no wash HTS-friendly protocols with a sensitive chemiluminescent read-out Multiple Assay Types – Binding and functional (direct and reporter-based) cell-based assay with no need for antibodies, fixing, or imaging Fast, Superior Results – Rapid assay with short compound incubation times, high signal-to-background, and no false positives High Specificity – Whole cell, non-ELISA assays with increased target specificityathway assays that enable you to measure distinct events within a variety of pathways associated with immune response, compound toxicity, cholesterol metabolism, antioxidant function, DNA damage, and more. Combined with a fast and simple chemiluminescent detection, these signaling pathway assays enable the generation of cellular pathway selectivity profiles and obtain a comprehensive understanding of different compounds or biologics for receptor-proximal or -distal events without relying on complex phenotypic screens.
Cell Line: ?
EXpress Kit:
Bioassay Kit生物檢測(cè)試劑盒:
Protein蛋白:
Cell Type細(xì)胞類型: NTCC? Signaling Pathway Stable Cell Line
Source組織來源:
Specification規(guī)格:
Cell Images細(xì)胞圖片:
Complete Growth Medium完全培養(yǎng)基: NTCC? IL11R STAT3 Stable Cells Complete Medium
Subculturing傳代方法:
Cryopreservation凍存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: RT/Liquid nitrogen vapor phase
Culture Conditions培養(yǎng)條件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鑒定數(shù)據(jù):
References參考文獻(xiàn):

Supplier供應(yīng)商:
BioVector質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心
NTCC典型培養(yǎng)物保藏中心
Tel電話：400-800-2947
Email：[email protected]
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