Cell Line Name：NTCC? HCN1 Ion Channel Stable Cell Line離子通道穩(wěn)定表達(dá)細(xì)胞株

Target藥物靶點(diǎn)：HCN1
Cat#貨號(hào):NTCC?-I-HCN1
Size/Quantity數(shù)量: 1 Flask / 2 Vials
Biosafety Level生物安全級(jí)別: 1
Shipping Info運(yùn)輸方式: RT/Dry Ice
Storage儲(chǔ)存方式: RT/Liquid Nitrogen
Application用途:Electrophysiological studies
High-Quality NTCC? PrecisION Cell Lines for Target Discovery, Hit Screening, Lead Optimization, and Safety Studies. Ion channels continue to be an important therapeutic target for a wide range of indications, including arrhythmia, hypertension, local anesthesia, pain, stroke, epilepsy, depression, bipolar disorder, cystic fibrosis, cardiac arrhythmias, COPD, autoimmune disorders, and diabetes. They are an appealing target to develop therapeutics against rare channelopathies, since many of these diseases are caused by the mutation of a single gene. Ion channels not only constitute a significant class of drug targets, they are also critical for evaluating drug safety, including being part of the U.S. FDA required safety testing for any drug targeted against human disease. NTCC?’s comprehensive portfolio of functionally validated ion channel products is comprised of optimized and NTCC?PrecisION stable ion-channel cell lines for use in cell-based assays, NTCC? PathHunter pharmacotrafficking assays for pharmacochaperone discovery, and an hERG ion channel membrane preps for binding studies. The vast ion channel product solutions include assessment of voltage-gated, ligand-gated, and several other targets for screening ion channel inhibitors for your drug discovery and safety applications. The ion channel cell lines are pharmacologically and functionally validated using in-house discovery and safety services laboratories. Their biophysical and pharmacological properties are characterized electrophysiologically using conventional manual patch-clamp and multiple automated patch-clamp platforms by experienced electrophysiologists in both BioVector NTCC Inc. services and BioVector NTCC Inc. products laboratories.
Cell Line: ?
Membrane Prep:
Bioassay Kit生物檢測(cè)試劑盒:
Other Collection No.其他編號(hào):
Cell Type細(xì)胞類型: Ion Channel Stable Cell Line
Source組織來(lái)源:
Specification規(guī)格:
Cell Images細(xì)胞圖片:
Complete Growth Medium完全培養(yǎng)基: NTCC? HCN1 Stable Cells Complete Medium
Subculturing傳代方法:
Cryopreservation凍存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: RT/Liquid nitrogen vapor phase
Culture Conditions培養(yǎng)條件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鑒定數(shù)據(jù):
References參考文獻(xiàn):

Supplier供應(yīng)商:
BioVector質(zhì)粒載體菌株細(xì)胞蛋白抗體基因保藏中心
NTCC典型培養(yǎng)物保藏中心
Tel電話：400-800-2947
Email：[email protected]
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