BioVector? yap1 yeast mutant strain酵母突變株

Standard Name
YAP1 1
Systematic Name
YML007W
SGD ID
SGD:S000004466
Aliases
PAR1 35 , SNQ3 32 , PDR4 22
Feature Type
ORF , Verified
Description
Basic leucine zipper (bZIP) transcription factor; required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; Yap1p is degraded in the nucleus after the oxidative stress has passed; mediates resistance to cadmium; relative distribution to the nucleus increases upon DNA replication stress; YAP1 has a paralog, CAD1, that arose from the whole genome duplication 2 3 4 5 6 7 8
Name Description
Yeast AP-1 3
Paralog
CAD1

Summary
YAP1 is located on the left arm of chromosome XIII near the centromere between MIN4 mitochondrial protein and GIS4 CAAX box protein; coding sequence is 1953 nucleotides long with a uORF at -84..-64 and 14 SNPs, 5 of which cause amino acid polymorphisms; YAP1 has paralog CAD1 from the whole genome duplication

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