HD10.6 Immortalized dorsal root ganglion (DRG) cell line永生化背根神經(jīng)節(jié)細胞株

Cell line name HD10.6
Comments Characteristics: Immortalized dorsal root ganglion (DRG) cell line that in the presence of doxycycline can differentiate into sensory neurons with nociceptive features (PubMed=10377351).

Characteristics: Susceptible to infection by herpes simplex virus 1 (HSV-1). A quiescent state resembling latency can be established in the HSV-1 infection in the presence of acyclovir (PubMed=28404842).
Doubling time: 1.2 days (PubMed=10377351).

Transfected with: UniProtKB; P01110; Avian myelocytomatosis virus MC29 v-Myc.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: v-Myc; tetracycline-regulated.

Derived from sampling site: Dorsal root ganglion. Cell type=Neuron.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell Male
Age at sampling <12fw<>Category Transformed cell line

Publications
PubMed=10377351; DOI=10.1523/JNEUROSCI.19-13-05420.1999
Raymon H.K., Thode S., Zhou J.-Y., Friedman G.C., Pardinas J.R., Barrere C., Johnson R.M., Sah D.W.Y.
Immortalized human dorsal root ganglion cells differentiate into neurons with nociceptive properties.
J.Neurosci. 19:5420-5428(1999)

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