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首頁 ? CHO-K1/BTLA BioVector NTCC質(zhì)粒載體菌種細(xì)胞基因保藏中心

CHO-K1/BTLA BioVector NTCC質(zhì)粒載體菌種細(xì)胞基因保藏中心

  • 價(jià)  格:¥998685
  • 貨  號(hào):CHO-K1/BTLA
  • 產(chǎn)  地:北京
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BioVector NTCC典型培養(yǎng)物保藏中心
聯(lián)系人:Dr.Xu, Biovector NTCC Inc.

電話:400-800-2947 工作微信:1843439339 (QQ同號(hào))

郵件:[email protected]

手機(jī):18901268599

地址:北京

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CHO-K1/BTLA


The B and T lymphocyte attenuator (BTLA) is an Ig super family protein with an intermediate type Ig fold in the ectodomain and an ITIM inhibitory signaling domain in the cytosol. BTLA interacts with the herpesvirus entry mediator (HVEM; TNFRSF14), a TNFR super family member. Engagement of BTLA by HVEM, induces tyrosine phosphorylation of the ITIM motifs in the cytoplasmic tail of BTLA, allowing the recruitment of the phosphatases SHP-1 and SHP-2, which attenuate signaling.

Synonyms
BTLA1; CD272

Supplier來源:BioVector NTCC Inc.
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