CHO-K1/M1 Stable Cell Line cell line穩(wěn)轉(zhuǎn)細胞株


M1 was expressed in the CNS such as cerebral cortex, basal ganglia, limbic areas, vestibular system and esophageal smooth muscle. Synaptic transmission by muscarinic acetylcholine receptors (mAChRs) is employed throughout the central and peripheral nervous systems to elicit a large and diverse array of neurophysiological actions. An important aspect of mAChR functional diversity is reflected by the multitude of biochemical and electrophysiological actions evoked by acetylcholine binding to mAChRs, which include the regulation of intracellular levels of cAMP, cGMP and inositol phospholipids, and the opening or closing of the potassium, calcium, and chloride ion channels found in certain tissues.

Synonyms
M1 receptor, m1, acetylcholine receptor, muscarinic 1, Cholinergic receptor muscarin 1, M1 muscarinic acetylcholine receptor, cholinergic receptor, muscarinic 1, m1 muscarinic acetylcholine receptor protein, muscarinic acetylcholine receptor M1, muscarinic acetylcholine receptor 1, Chrm-1, M1R, AW495047
Species Human
Freeze Medium 45% culture medium, 45% FBS (Cat. #10099-141, Gibco), 10% DMSO (Cat. #D2650, Sigma)
Culture Medium Ham’s F-12K (Kaighn’s), 10% FBS, 200 ug/ml Zeocin (Cat. #R250-01, Life Technologies)
Properties
Storage Liquid nitrogen immediately upon delivery
Applications
Functional assay for M1 receptor

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