TOPFlash質(zhì)粒載體圖譜序列抗性說明書價格Biovector公司
- 價 格：￥2920
- 貨 號：BiovectorOPFlash
- 產(chǎn) 地：北京
- BioVector NTCC典型培養(yǎng)物保藏中心
- 聯(lián)系人：Dr.Xu, Biovector NTCC Inc.
電話：400-800-2947 工作微信:1843439339 (QQ同號)
手機(jī)：18901268599
地址：北京
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載體基本信息
| 出品公司: | Millipore |
|---|---|
| 載體名稱: | TOPFlash |
| 質(zhì)粒類型: | 信號通路報告系統(tǒng)載體 |
| 高拷貝/低拷貝: | -- |
| 啟動子: | -- |
| 克隆方法: | 多克隆位點(diǎn)，限制性內(nèi)切酶 |
| 載體大小: | -- |
| 5' 測序引物及序列: | -- |
| 3' 測序引物及序列: | -- |
| 載體標(biāo)簽: | -- |
| 載體抗性: | Ampicillin |
| 篩選標(biāo)記: | -- |
| 備注: | -- |
| 產(chǎn)品目錄號: | 21-170 |
| 穩(wěn)定性: | -- |
| 組成型: | -- |
| 病毒/非病毒: | -- |
載體質(zhì)粒圖譜和多克隆位點(diǎn)信息
載體簡介
The Wnt/Wg family encodes secreted glycoproteins implicated in cell growth regulation, cell fatedetermination, organogenesis and oncogenesis. Inferred from genetic analysis of wingless (wg) signaling inDrosophila, in mammalian cells, Wnts signal through the Frizzled family of receptors, to Dishevelled. Dishevelleddown regulates glycogen synthase kinase-3 (GSK-3 ) activity. This results in the stabilization and accumulation ofcytosolic -catenin, a GSK-3 substrate, which when phosphorylated by GSK-3, is targeted for ubiquitin-mediatedproteolysis. -catenin then translocates to the nucleus, where in complexes with members of the Tcf/LEF family oftranscription regulators, activates transcription of Tcf-responsive genes. This Tcf-reporter plasmid, along withFOPFLASH (Cat. # 21-169) enables quantitation of Wnt/Wg signaling in cells transfected with these constructs.您正在向 biovector.net 發(fā)送關(guān)于產(chǎn)品 TOPFlash質(zhì)粒載體圖譜序列抗性說明書價格Biovector公司 的詢問
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